(Fabaceae-Papilionoideae) Millettia pachyloba Drake

Local name(s): ເຄືອຫໍາງົວ (Kheua ham ngua)

Medicinal use(s): detoxification caused by eating allergic food during puerperium

Part(s) used: vine without bark

Field Characters: Liana, leaves pinnate, leaflets 5-9, legume brown, short-hairy, seeds deep brown, shiny. 

Locality: Oudomxay, Muang Xay District, Donxay Village, Medicinal Biodiversity Preserve, about 3 km south of the city. GPS reading: At the vicinity of 20o 40.0181’ N; 102o 00.155’ E.

Habitat: Forested slope in a broadleaved, mixed evergreen lowland tropical rainforest on a mountain slope.

Altitude: 800-900 m asl 

Collector(s): D.D. Soejarto, K. Sydara, M. Xayvue 

Collection number(s): DDS 15097

Collection Date: September 26, 2014

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Local name(s): (kheua khee ha khuay)

Medicinal use(s): used as a tonic.

Part(s) used: root

Field Characters: Liana, inflorescences and branches brown-pubescent, fruits covered with brown velvety pubescence.

Locality: Bolikhamxay Province, Paksan district, Somsavath Village, Medicinal Plant Preserve, at 20 km from Paksan city center.

Habitat: Secondary forest. Remnants of broadleaved evergreen, lowland tropical rain forest, in regeneration from past conversion process.

Altitude: 190 m asl 

Collector(s): D.D. Soejarto & O. Souliya 

Collection number(s): DDS 15009

Collection Date: May 24, 2014

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Local name(s): (ຫ່າຄວາຍ; ຍ່ຽວຄວາຍ; ຍ່າທູ້) (Ha khouay; Nhiew Khoury; Nha thou)

Medicinal use(s): treat intestinal hemorrhoids, kidney stone

Part(s) used: stem

Field Characters: Climber on a tree, leaves compound, flowers pink, fragrant.

Locality: Dong na tat forest preserve, km 19,  Kaisonephomvihan district, Savannakhet province

GPS reading: 16o 39.313’ N; 104o 51.947’ E.

Habitat: Broadleaved evergreen lowland tropical rainforest, with some degree of past conversion. 

Altitude: 160 m asl.

Collector(s): K. Sydara, M. Xayvue, Th. Sonemanyvong 

Collection number(s): KS 19-001

Collection Date: March 24, 2014

Additional information:  

Synonyms, images, taxonomic description: 

Useful references:

 Jena R, Rath D, Rou SS, Kar DM. A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities. Saudi Pharm J. 2020, 28(12):1686-1703. doi: 10.1016/j.jsps.2020.10.015. Epub 2020 Nov 5. PMID: 33424261; PMCID: PMC7783215.

 Kamto ELD, Kamdem BP. Pharmacological Activity and Mechanism of Action of Flavonoids from Diverse Millettia Plant Organs. The Natural Products Journal 2022, volume 12, Issue 7. Article ID: e090522204421, pages: 29. DOI: 10.2174/2210315512666220509114733

Xie Z, Cheng X, JianCang Mao JC. Extracellular vesicles enhance the in vivo antitumor effects of Millettia species-derived compounds in chronic myelogenous leukemia therapy. Front. Chem. 2024, Sec. Medicinal and Pharmaceutical Chemistry Volume 12. https://doi.org/10.3389/fchem.2024.1425318

 Yan W, Yang J, Tang H, et al. Flavonoids from the stems of Millettia pachyloba Drake mediate cytotoxic activity through apoptosis and autophagy in cancer cells. J Adv Res. 2019, 20:117-127. doi: 10.1016/j.jare.2019.06.002. PMID: 31338224; PMCID: PMC6626068.