(Piperaceae) Piper laetispicum C. DC. 

Local name(s): ໝາກ ຂີ້ ໄກ່ ປ່າ (mak khee kai pa)

Medicinal use(s): urinary tract infection, kidney stones 

Part(s) used: root

Field Characters: Vine. 

Locality: Sekong Province, Thateng District, Pa Leng Tai Village, Sekong MBP Thateng 

Habitat: Sekong MBP Thateng; secondary forest, on slope above stream, soil dry, sandy. Shaded. 

Altitude: 520 m asl 

Collector(s): M. Xayvue, S. Setthavanxay, B. Elkington 

Collection number(s): BGE 279

Collection Date: November 19, 2019

Local name(s): (Kheua phak I leut; I leut dong; Phik thai pa)

Medicinal use(s): treat gonorrhea 

Part(s) used: whole plant

Field Characters: Epiphytic climber, attaching to a large tree-trunk, fruits green, set n a helical infructescence.

Locality: Oudomxay, Muang Xay District, Donxay Village, Medicinal Biodiversity Preserve, about 3 km south of the city.

GPS reading: At the vicinity of 20o 40.0181’ N; 102o 00.155’ E.

Habitat: Forested slope in a broadleaved, mixed evergreen lowland tropical rainforest on a mountain slope.

Altitude: 750-800 m asl. 

Collector(s): D.D. Soejarto, K. Sydara, M. Xayvue 

Collection number(s): DDS 1096

Collection Date: September 26, 2014

Additional information:  

Synonyms, images, taxonomic description: 

Useful references:

Ding X, Chen W, Jiang Y, et al. Piper laetispicum extract and preparation method therefor and use thereof. Patent: US 20210187051 A1. Applicant : SUZHOU YI - HUA BIOMEDICAL TECHNOLOGY CO., LTD , Suzhou (CN). https://patentimages.storage.googleapis.com/92/5e/89/90e9db122f58f9/US20210187051A1.pdf

 Salehi B, Zakaria ZA, Gyawali R, et al.  (2019). Piper Species: A comprehensive review on their phytochemistry, biological activities and applications. Molecules 2019, 24(7): 1364. Published online Apr 7. doi: 10.3390/molecules24071364 https://doi.org/10.3390/molecules24071364

 Stöhr JR, Xiao P-G, Bauer R. Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene biosynthesis in vitro. Journal of Ethnopharmacology 2001, Volume 75, Issues 2–3, Pages 133-139. ISSN 0378-8741. https://doi.org/10.1016/S0378-8741(00)00397-4. (https://www.sciencedirect.com/science/article/pii/S0378874100003974)

 Xie H, Jin D, Kang Y, et al. The effect of Piper laetispicum extract (EAE-P) during chronic unpredictable mild stress based on interrelationship of inflammatory cytokines, apoptosis cytokines and neurotrophin in the hippocampus. BMC Complement Altern Med 15, 240 (2015). https://doi.org/10.1186/s12906-015-0747-8