(Apocynaceae) Melodinus cochinchinensis (Lour.) Merr.

Local name(s): ເຄືອ ຫມາກ ຢາງ (kheua mak yang)

Medicinal use(s): 

Part(s) used: 

Field Characters: Vine, latex milky white, flowers paper-white.

Locality: Bolikhamxay Province, Paksan District, Somsavath Village, Medicinal Plant Preserve.

Habitat: 26 Hectare remnants of forest on flat terrain, with many species of large trees still remaining.

Altitude: 150 m asl. 

Collector(s): D. Soejarto 

Collection number(s): DDS 13505

Collection Date: July 18, 2004

Additional information:  

Voucher specimen is in deposit at the Field Museum (F) Herbarium, Chicago, USA under accession no. 2275343.

Synonyms, images, taxonomic description: 

Plants of the World onlineFlora of China Vol. 16 Page 149

Useful references:

Liu Y-P, Li Y, Xiang-Hai Cai X-H. Melodinines M–U, Cytotoxic Alkaloids from Melodinus suaveolens. J. Nat. Prod.. 2012, 75, 2, 220–224. https://doi.org/10.1021/np2009169 

Lu Y, Khoo TJ, C. Wiart C. The Genus Melodinus (Apocynaceae): Chemical and Pharmacological Perspective. Pharmacology and Pharmacy 2014, volume 5, issue 5, pages 540-550. ISSN Print: 2157-9423. ISSN Online: 2157-9431. DOI: 10.4236/pp.2014.55064  


Teng Si-F, Li F-R, Cui Q-M, et al. (2023). A review on the genus Melodinus: traditional uses, phytochemical diversity and pharmacological activities of indole alkaloids. Phytochemistry Reviews 2023, 1-54. DOI:10.1007/s11101-023-09871-2 
Yang L, He J-J, Cui XY, et al. Chemical constituents from Melodinus cochinchinensis (Lour.) Merr. and their chemotaxonomic significance,Biochemical Systematics and Ecology 2021, volume 95, 104245.ISSN 0305-1978. https://doi.org/10.1016/j.bse.2021.104245.

Yang M, Wang Y, Fan Z, et al. Chemical constituents and anti-inflammatory activity of the total alkaloid extract from Melodinus cochinchinensis (Lour.) Merr. and its inhibition of the NF-κB and MAPK signaling pathways. Phytomedicine 2021,  91:153684. DOI: 10.1016/j.phymed.2021.153684