(Fabaceae) Millettia pachyloba Drake

Local name(s): ເຄືອ ຫໍາ ງົວ (kheua ham ngua)

Medicinal use(s): detoxification caused by eating allergic food during puerperium

Part(s) used: vine without bark

Field Characters: Liana, leaves pinnate, leaflets 5-9, legume brown, short-hairy, seeds deep brown, shiny. 

Locality: Oudomxay, Muang Xay District, Donxay Village, Medicinal Biodiversity Preserve, about 3 km south of the city. 

Habitat: Forested slope in a broadleaved, mixed evergreen lowland tropical rainforest on a mountain slope.

Altitude: 800-900 m asl 

Collector(s): D.D. Soejarto, K. Sydara, M. Xayvue 

Collection number(s): DDS 15097

Collection Date: September 26, 2014

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Local name(s): (kheua khee ha khuay)

Medicinal use(s): used as a tonic.

Part(s) used: root

Field Characters: Liana, inflorescences and branches brown-pubescent, fruits covered with brown velvety pubescence.

Locality: Bolikhamxai Province, Paksan District, Somsavath Village, Medicinal Plant Preserve, at 20 km from Paksan city center.

Habitat: Secondary forest. Remnants of broadleaved evergreen, lowland tropical rain forest, in regeneration from past conversion process.

Altitude: 190 m asl 

Collector(s): D.D. Soejarto & O. Souliya 

Collection number(s): DDS 15009

Collection Date: May 24, 2014

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Local name(s): ຫ່າ ຄວາຍ (ha kouai) ; ຍ່ຽວ ຄວາຍ (niao kouai) ; ຍ່າ ທູ້ (nya tou)

Medicinal use(s): treat intestinal hemorrhoids, kidney stone

Part(s) used: stem

Field Characters: Climber on a tree, leaves compound, flowers pink, fragrant.

Locality: Dong na tat forest preserve, km 19,  Kaisonephomvihan district, Savannakhet province

Habitat: Broadleaved evergreen lowland tropical rainforest, with some degree of past conversion. 

Altitude: 160 m asl.

Collector(s): K. Sydara, M. Xayvue, Th. Sonemanyvong 

Collection number(s): KS 19-001

Collection Date: March 24, 2014

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Local name(s): ຫ່າ ຄວາຍ (ha kouai) ; ຍ່ຽວ ຄວາຍ (niao kouai) ; ຍ່າ ທູ້ (nya tou)

Medicinal use(s): treat intestinal hemorrhoids, kidney stone

Part(s) used: stem

Field Characters: Climber on a tree, leaves compound, flowers pink, fragrant.

Locality: Dong na tat forest preserve, km 19,  Kaisonephomvihan district, Savannakhet province

Habitat: Broadleaved evergreen lowland tropical rainforest, with some degree of past conversion. 

Altitude: 160 m asl.

Collector(s): K. Sydara, M. Xayvue, Th. Sonemanyvong 

Collection number(s): KS 19-001

Collection Date: March 24, 2014

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Local name(s): ເຄືອຍ່ຽວຄວາຍ (Kheu nyiav khuai)

Medicinal use(s): used as a laxative 

Part(s) used: vine (stem)

Field Characters: Liana with compound leaves, leaflets in four pairs, fruits a legume, hairy. 

Locality: Khammuan Province; Nyommalath District; Thongkong Village, forest roadside of Route to Khammouane Medicinal Biodiversity Preserve; at the southern reaches of Nakai Nam Theum National Park. 

Habitat: Tropical rainforest on flat level lands. 

Altitude: 150 m asl.

Collector(s):  O. Souliya, K. Phoulivong, D. Makiem and S. Pimmavong 

Collection number(s):  Onevilay_YML_004

Collection Date: July 21, 2023.

Additional information:  

Synonyms, images, taxonomic description: 

Medicinal properties:

 Jena R, Rath D, Rou SS, Kar DM. A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities. Saudi Pharm J. 2020, 28(12):1686-1703. DOI: 10.1016/j.jsps.2020.10.015

 Kamto ELD, Kamdem BP. Pharmacological Activity and Mechanism of Action of Flavonoids from Diverse Millettia Plant Organs. The Natural Products Journal 2022, volume 12, Issue 7. Article ID: e090522204421, pages: 29. DOI: https://doi.org/10.2174/2210315512666220509114733 

Xie Z, Cheng X, JianCang Mao JC. Extracellular vesicles enhance the in vivo antitumor effects of Millettia species-derived compounds in chronic myelogenous leukemia therapy. Front. Chem. 2024, Sec. Medicinal and Pharmaceutical Chemistry Volume 12. https://doi.org/10.3389/fchem.2024.1425318 

 Yan W, Yang J, Tang H, et al. Flavonoids from the stems of Millettia pachyloba Drake mediate cytotoxic activity through apoptosis and autophagy in cancer cells. J Adv Res. 2019, 20:117-127.  DOI: 10.1016/j.jare.2019.06.002